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What is venlafaxine? venlafaxine dosage, is an antidepressant belonging to a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Venlafaxine affects chemicals in the brain that may be unbalanced in people with depression. Venlafaxine is a prescription medicine used to treat major depressive disorder, anxiety, and panic disorder. Warnings You should not …